In this paper we describe the advances made in high accuracy, high performance destination color profiling technology for use in digital printers. A profiling technology, configured to produce (a) an initial estimate in the factory of a fine tuned GCR strategy and gain matrices as starting LUTs, and (2) a runtime profiling technology for adjusting colors before production run by the customer on a drifted print engine. Key new algorithms presented are: Co-operative Neighbor Driven Gray Component Replacement (GCR) algorithm and control-based inversion. These algorithms are used with other known suite of algorithms to make a complete practical profiling technology.