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Volume: 32 | Article ID: art00006
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Soft-prototyping imaging systems for oral cancer screening
  DOI :  10.2352/ISSN.2470-1173.2020.7.ISS-212  Published OnlineJanuary 2020
Abstract

We are using image systems simulation technology to design a digital camera for measuring fluorescent signals; a first application is oral cancer screening. We validate the simulations by creating a camera model that accurately predicts measured RGB values for any spectral radiance. Then we use the excitationemission spectra for different biological fluorophores to predict measurements of fluorescence of oral mucosal tissue under several different illuminations. The simulations and measurements are useful for (a) designing cameras that measure tissue fluorescence and (b) clarifying which fluorophores may be diagnostic in identifying precancerous tissue.

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Joyce Farrell, Zheng Lyu, Zhenyi Liu, Henryk Blasinski, Zhihao Xu, Jian Rong, Feng Xiao, Brian Wandell, "Soft-prototyping imaging systems for oral cancer screeningin Proc. IS&T Int’l. Symp. on Electronic Imaging: Imaging Sensors and Systems,  2020,  pp 212-1 - 212-7,  https://doi.org/10.2352/ISSN.2470-1173.2020.7.ISS-212

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