Seeing 600th anniversary of Gutenberg's birth in 2000 A.D., we should look back the historical significance of letterpress technology and take a step forward into color imaging new age. Now digital imaging technology plays a leading role in visual communication, but meets severe assessment to satisfy human vision. Software on “What's human vision seeing?” is essential to capture, store, transmit, and reproduce a truly realistic image just as human vision seeing. Not only advances in high precision and high definition digital media, but also Intelligent Image Processing technologies will be helpful for more aesthetic and pleasant imaging. We are approaching towards this direction from a stance of engineering to use the scientific results in human vision research. This paper introduces just a little “intelligent” processing to “image sharpening”, “local contrast enhancement”, and “color transform” by region-based, spatially-variant, and scene-referred approaches.