PUR (PolyUrethane Reactive) adhesives have been available for decades, but have been in bookbinding primarily since 1989. PUR has been chosen over standard hot melt and liquid adhesives for many reasons. These reasons include adhesion, layflat of the book, heat and cold resistance, roundability and durability. Applications systems have improved reducing the overall cost of production. Even though the price per pound of PUR is higher than that of other adhesives, the cost per unit is comparable. Initial concerns centered around one of the components, MDI, but this has proven over the last 20 years to be a minimal concern. The future of PUR is bright. As newer versions emerge additional markets are opening. Some of those markets include photo albums and hard cover books.
Charles W. Cline, "A Place for PUR in the Bindery" in Proc. Int'l Symp.on Technologies for Digital Photo Fulfillment, 2012, pp 28 - 30, https://doi.org/10.2352/ISSN.2169-4672.2012.3.0.1