To explore effects of geometric features on color similarity perception of displayed 3D tablets designed by color 3D modeling techniques or printed by color 3D printing techniques, two subjective similarity scaling tasks were conducted for color tablets with four shape features (circular-, oval-, triangular columnar- and rounded cuboid-shaped) and four notch features (straight V-, straight U-, crisscross V- and crisscross U- shaped) displayed on the calibrated monitor using nine-level category judgement method. Invited observers were asked to classify each specific sample in tablet groups using six surface colors (aqua blue, bright green, pink, orange yellow, bright red and silvery white), and recorded all perceived similarity values compared to original samples successively. A fact that the similarity perception of tested tablets was inapparently affected by given shape features and notch features, should judge by a flexible interval rather than a fixed color difference. This research provides a practical insight into vision visualization of color similarity perception for displayed personalized tablets to achieve further precision medicine.