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Volume: 32 | Article ID: art00107_1
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Fabrication of ZrO2-SiO2 binary oxide Scaffold for Bone Tissue Engineering applications
  DOI :  10.2352/ISSN.2169-4451.2017.32.429  Published OnlineSeptember 2016
Abstract

Musculoskeletal disorders and bone defects have been established as one of the most important diseases affecting human health. The occurrence of bone defects due to the growing number of traffic accidents and osteoporosis have led to demand for mass numbers of bone implants. ZrO2-SiO2 binary oxide as a potential candidate with the features of mechanical strength and biocompatibility that precisely mimic the host bone has been synthesized using so-gel technique (1). Fabrication of ZrO2-SiO2 binary oxides into 3D porous scaffold is essential for structural stability of the bone implant enables them as a substrate for cells, growth factors and waste removal through their interconnected pores. Stereo lithography (SL) is one the most efficient Rapid Prototyping (RP) technique that has been adopted to fabricate 3D ceramic scaffolds with controlled architecture of desired shape, pore size and interconnectivity (2). The printed scaffold has been analysed for its surface morphology, porosity and interconnectivity through Scanning Electron Microscopy. The mechanical stability of the scaffold has been assessed using compression and bending strength tests.

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Vasanthavel Subramaniyan, Kannan Sanjeevi, Brian Derby, "Fabrication of ZrO2-SiO2 binary oxide Scaffold for Bone Tissue Engineering applicationsin Proc. IS&T Printing for Fabrication: Int'l Conf. on Digital Printing Technologies (NIP32),  2016,  https://doi.org/10.2352/ISSN.2169-4451.2017.32.429

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