As for the limitation of cartography technique, printing craft and network technique, map publishing information usually transmits in the unidirectional way, and the publishing cycle lasts long and users cannot participate in cartography, which cannot meet users' needs of individuation. In order to settle these problems, a new map publishing mode which is based on map customization service considering user interest is put forward. Corresponding techniques and solving strategies are discussed, including the manuscript database of map publishing and the application of multi-source data, user interest GIS analysis and disposal, cross-media map color control, the constitute of variable data and the optimal choice of digital printing site, etc. It provides important reference for the convert of map publishing mode from traditional one to map customization service mode based on User Interest. This mode comprehensively uses digital cartography technique, network publishing technique and digital printing technique, which lays emphasis on users' participation in the process of cartography and accords with the thought of individuation service for users.