The adhesion of two different solid surfaces can be predicted from their ability to induce spontaneous spreading of high surface tension liquids, because interfacial forces govern both the processes. The friction behavior of solid surfaces, on the other hand, is controlled by the interfacial dynamics, which has some features that are common to the sliding behavior of a liquid drop on a solid surface.Our work consisted of making polyamide and acid cured polyamides coatings. They were indented at different depths using a nanoindenter. It is well known that strain softening and strain hardening are analyzed by the effect of modulus and hardness on depth. Elastic plastic model has been used to analyze strain softening or strain hardening. Glass transition and molecular weight are important variables that affect strain dependence on modulus and hardness. In the polyamides and cross-linking polyamides, strain hardening is shown along with significant increase in modulus reduction in coefficient of friction. The results are applied to models of adhesion between toner and photoreceptor and it is shown that experimental results are consistent with the model predictions.