We present for the first time here that the micro-lens array is designed and fabricated with water-type polymer by inkjet printing technology. The micro-lens is, but not limited to be, simply designed with convex shape and small size less than 300 micrometers; the column and row of array cab be up to 100 × 100 and more. Meanwhile, by hydrophobic surface treatment of the substrate, micro-lens array is able be formed onto without coffeering. The specific fluid material of lens is formulated with low viscous solution of water-born Polyurethane (PU). Its optical refractive-index n is about 1.5. We also develop a new inkjet printing system that can generate droplets of such PU solution and deposit them onto the desired positions. Consequently, the dried solid micro-lens array is successfully fabricated after solvents completely drying. Many industrial applications for those microlens arrays can be found in LED package, LCD components, optical fiber component, and so on.