The wireless capsule would have been more comfortable for the patients than the traditional endoscope. The wireless capsules, such as Heidelberg capsule, pH capsule or the M2A capsule, just would be the diagnostic tool. However, the M2A capsule only uses as the image sensor to find the nidus. It only sends the image data to the record outside the body. If the capsule could take the drugs to the intestine and jet to the nidus, it would reduce the pains of the patient. The advantage of the ink-jet technology is jet liquid to the target quantitatively and accurately. The present would show the inkjet technology applied on the capsule endoscope system which also includes the imager, illumination source, microlens, two-way wireless module. There are ink-jet type micro actuator, medicine tank, and control circuit in the medicine-jet subsystem. The micro actuator can jet medicine droplets by the droplet-on-demand. The droplet volume could be few Pico-liters. Since the characteristic of the ink-jet technology, the medicine could be put in the medicine tank of the swallow capsule, brought to the ridus and jetted.