The work studies the impact of five structural parameters on the compressive strength of corrugated octagonal trays: aspect ratio, handle position, handle width, hypotenuse length, and hypotenuse angle. It aims at enhancing the design of fruit and vegetable paper tray packaging. Initial single-factor experiments established the influence of these parameters on compressive strength. Subsequent orthogonal testing and comprehensive analysis optimized the tray design. Notably, compressive strength peaks at a hypotenuse angle of 145∘ and a hypotenuse length of 60 mm. The strength also peaks at an aspect ratio of approximately 1.4:1. The optimal performance is achieved with a hypotenuse length of 65 mm, handle width of 25 mm, handle position at HL, a hypotenuse angle of 145∘, and an aspect ratio of 1.2:1. These findings underscore the importance of these parameters in tray design for maximum compressive strength.