The study focuses on the fresh-keeping effect of clove packaging carton on strawberries as well as the preservation and physical properties of the carton. The extraction conditions were optimized by orthogonal test method, and the components of clove extract were analyzed by gas chromatography-mass spectrometry (GC-MS). The physical properties of packaging cartons and the preservation performance of strawberries were studied by comparative experiments. With an increase in the coating amount of clove extract, the empty carton’s compressive strength, bursting strength and edge compressive strength of the carton show a downward trend as a whole, but remain above 85% of the original carton strength, which can meet the needs of use. When the coating amount of clove extract is 150 mL/m², the preservation performance is the best. At this level, the weight loss rate of strawberry is 34.96%, the soluble solid content is 8.0%, and the titratable acid content is 25%. According to the physical properties and preservation properties of clove extract packaging cartons, the carton with a coating amount of 150 mL/m² is best suited for meeting food industry’s needs.