In recent years, the incidence of diseases such as uterine fibroids in women in China has increased, which has raised people’s attention to the clinical effects and postoperative recovery effects of medical gynecological surgery. Regarding gynecological surgery, there are many types of myomectomy, and among them, vaginectomy is receiving widespread attention in gynecological surgery. This article studies the clinical effects of laparoscopic imaging technology-assisted vaginal resection and the functional status, mental status, and hormone levels of women during the recovery period, and analyzes the postoperative ovarian function and immune function of women. In this article, 111 patients with uterine fibroids were divided into the observation group and the reference group, of which 56 cases were in the reference group and 55 cases were in the observation group. The hospital stay, ovarian function status, immune status, uterine recovery, and tibia recovery of the control group and the experimental group were respectively analyzed. In the experiment, laparoscopic imaging technology-assisted vaginal resection surgery has no incision pain. It can be moved early on the ground and can be discharged within 2–4 days after surgery. This reduces medical expenses to a certain extent and can be performed at the same time without changing the position. This also performs other operations on the perineum or vagina, such as repairing the front and back walls of the vagina. Experimental results show that laparoscopic imaging technology-assisted vaginal resection can reduce pain and speed up the recovery of ovarian function. Three months after surgery, 59.6% of patients resumed ovulation, much higher than 42.3% in the control group. Vaginectomy using laparoscopic imaging technology can improve immunity by adjusting hormone levels in the body in a short time.