Due to the advancement in inkjet digital printing, it is possible to print spot color short run jobs with high quality and desired level of consistency in color at low cost. Mostly in the packaging industry, specific color is used for specific requirements of a customer, which is called a spot color. About 40% of packaging jobs are printed by flexo, 30% by offset lithography, 22% by rotogravure, and 8% by digital and other printing processes. The aim and purpose of this work was to investigate the proof color matching capability of two ink jet digital printers, differing in ink technology and prepress color matching software used, for spot color matching printed on a narrow web flexographic printing press. The results were produced by evaluating color differences between the colorimetric measurements from the flexographic printing press versus the digitally reproduced proofs from the two tested ink jet devices.