Digital transformation of commercial print production brings new opportunities including exploitation of embedded sensing and computing power that enable real-time communication during various phases of the production chain and dynamic reconfiguration of production flow. Simulation based modeling can help to exploit these opportunities at both strategic and operational levels. In this article we report our ongoing work on simulating an end-to-end print production process. We draw a close parallel between print production design and electronic design automation, and model print production system as a network of interconnected, distinct processes. We describe our simulation framework, simulation validation against queuing network theory, preliminary simulation results, and path to policy design and analysis.