Mapping pigmentation in human skin is expected to give useful information in reproducing skin color and enhancing the ability to diagnose various skin disease. In this research, maps of melanin, oxy-hemoglobin and deoxy-hemoglobin in skin are estimated from multi-channel visible spectrum image by using an inverse optical scattering technique. In the inverse optical scattering technique, first of all, a forward model of optical scattering is built to simulate the spectral reflectance of skin. Changing the variable parameters in the forward model, we repeat the simulation until the simulated spectral reflectance matches with the spectral reflectance at each pixel of the multi-spectral image. The principle of the proposed estimation technique was confirmed by imaging the human forearm under conditions of the venous occlusion, the venous and arterial occlusion, and by imaging a slapped region of the human forearm.
Norimichi Tsumura, Miki Kawabuchi, Hideaki Haneishi, Yoichi Miyake, "Mapping Pigmentation in Human Skin from a Multi-Channel Visible Spectrum Image by Inverse Optical Scattering Technique" in Journal of Imaging Science and Technology, 2001, pp 444 - 450, https://doi.org/10.2352/J.ImagingSci.Technol.2001.45.5.art00005