Mixed Reality (MR) introduces many possibilities for interacting with virtual environments in which training could be provided for some life-saving critical tasks. Neonatal Resuscitation is one of these tasks that would benefit from having a safe and immersive environment for practice. In this paper, we introduce an MR-based simulation that is aimed at healthcare practitioners to practice Positive Pressure Ventilation (PPV) in an immersive, risk-free, and interactive way using the hand-tracking capabilities built in the Mixed Reality Head Mounted Display. This research moves towards providing a standard addition to the neonatal healthcare system where MR could facilitate refresher sessions for the neonatal resuscitation procedure and eventually allow practitioners to assess their performance during the simulation. The simulation is based on a Virtual Reality (VR) Neonatal Resuscitation Program (NRP) simulation and is designed to rely on and utilize MR elements and features. We propose that this simulation could be used to receive refresher training sessions that would take place between the regularly scheduled in-person training sessions.