In this study, two experiments were conducted to assess the importance of using individual color matching functions (CMFs) for cross-media color reproduction. Firstly, five observers used a visual trichromator to perform a series of color matches. Using the extended CIEPO006 model, these matches were used to derive estimates of each individual’s CMFs. Each observer repeated the experiment five times to assess intra-observer variability. Subsequently, the same observers performed cross-media color reproduction experiments using a cross-media color matching system. The findings indicated that the individual CMFs can provide much more accurate predictions of the visual results than the standard CIE CMFs. Thus, individual CMFs can greatly enhance the accuracy of color reproduction.