Environmental friendly materials have aroused great attention. Lithography printing takes the most important position in traditional printing industry. So far, it is still a great challenge for lithography printing to use water based inks for mass production. Here we report the integration of green plate, green plate-making technology and water based ink to achieve water based lithography. The main problem is how to get a clear hydrophilic and hydrophobic area discrepancy on the printing plate. The key is to control the surface energy in micro-area on the printing plate. Nano materials have been developed to achieve this water based lithography.