Smartphones with 100 million pixel sensor are on the market. After that, it is expected to mount a higher resolution mobile camera module of 200 million pixels or more. In order to develop high resolution sensor products by mounting more pixels in a limited space, it is necessary to reduce the size of the pixels. There are currently sensors on the market with 0.64um pixels. It is expected that sensors with smaller pixels will be developed in the future. In terms of image quality, the smaller the pixel size, the smaller the amount of light received. Therefore, the image quality deteriorates in terms of noise and crosstalk. To overcome this limitation, various high sensitivity sensors are being developed, and it is advantageous to mount Nano Prism in the development of high sensitivity sensor. In this paper, we introduce the image quality performance of CMOS image sensor equipped with Nano Prism.