Real-time mapping pigmentation in human skin is expected to give useful information for reproducing various skin colors and monitoring human conditions in real time. In this research, the maps of melanin, oxy-hemoglobin and deoxy-hemoglobin densities in skin are estimated and displayed in real time from digital video signals by using three precomputed look up tables for color conversions. As the experiments to show the effectiveness of the proposed system, time dependent changes of pigmentation map in human hand are observed during the occlusion and release of middle finger, also during anaerobic by squat exercise. From the results of the experiments, human homeostasis for disturbance can be observed in real time.